Article
Persistent Staphylococcus aureus isolates from two independent cases of bacteremia display increased bacterial fitness and novel immune evasion phenotypes.
Infection and immunity - 1 Aug 2015
Richards R L, Haigh R D, Pascoe B, Sheppard S K, Price F, Jenkins D, Rajakumar K, Morrissey J A
Abstract excerpt
Staphylococcus aureus bacteremia cases are complicated by bacterial persistence and treatment failure despite the confirmed in vitro susceptibility of the infecting strain to administered antibiotics. A high incidence of methicillin-resistant S. aureus (MRSA) bacteremia cases are classified as persistent and are associated with poorer patient outcomes. It is still unclear how S. aureus evades the host immune...
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