Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yeast Fex1p Is a Constitutively Expressed Fluoride Channel with Functional Asymmetry of Its Two Homologous Domains.

The Journal of biological chemistry - 7 Aug 2015

Smith Kathryn D, Gordon Patricia B, Rivetta Alberto, Allen Kenneth E, Berbasova Tetyana, Slayman Clifford, Strobel Scott A

Abstract excerpt

Fluoride is a ubiquitous environmental toxin with which all biological species must cope. A recently discovered family of fluoride export (FEX) proteins protects organisms from fluoride toxicity by removing it from the cell. We show here that FEX proteins in Saccharomyces cerevisiae function as ion channels that are selective for fluoride over chloride and that these proteins are constitutively expressed at the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Resistance, Fungal
Share to Fluorides

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genome, Fungal

Share to Ion Transport

Share to Patch-Clamp Techniques

Share to Protein Folding

Share to Protein Multimerization

Share to Static Electricity

Source

Open in PubMed Open full text

Identifiers

PMID: 26055717
DOI: 10.1074/jbc.M115.651976
PMCID: PMC4528147

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yeast Fex1p Is a Constitutively Expressed Fluoride Channel with Functional Asymmetry of Its Two Homologous Domains.PMID 26055717Read ↗

Channeling studies in yeast: yeast as a model for channelopathies?Semantic proximity Read ↗

F-/Cl- selectivity in CLCF-type F-/H+ antiporters.Semantic proximity Read ↗

Fluoride export is required for competitive fitness of pathogenic microorganisms in dental biofilm modelsSemantic proximity Read ↗

A yeast metal resistance protein similar to human cystic fibrosis transmembrane conductance regulator (CFTR) and multidrug resistance-associated protein.Semantic proximity Read ↗

Engineering a human P2X2 receptor with altered ligand selectivity in yeast.Semantic proximity Read ↗

The yeast penta-EF protein Pef1p is involved in cation-dependent budding and cell polarization.Semantic proximity Read ↗

A generic high-throughput assay to detect aquaporin functional mutants: Potential application to discovery of aquaporin inhibitors.Semantic proximity Read ↗

The yeast CLC protein counteracts vesicular acidification during iron starvation.Semantic proximity Read ↗

Divergence of the yeast transcription factor FZF1 affects sulfite resistance.Semantic proximity Read ↗

Functional genomics: lessons from yeast.Semantic proximity Read ↗

Adaptive evolution by mutations in the FLO11 gene.Semantic proximity Read ↗

Evidence for iron channeling in the Fet3p-Ftr1p high-affinity iron uptake complex in the yeast plasma membrane.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.