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The Emerging Roles of Viroporins in ER Stress Response and Autophagy Induction during Virus Infection

4 Jun 2015

Abstract excerpt

Viroporins are small hydrophobic viral proteins that oligomerize to form aqueous pores on cellular membranes. Studies in recent years have demonstrated that viroporins serve important functions during virus replication and contribute to viral pathogenicity. A number of viroporins have also been shown to localize to the endoplasmic reticulum (ER) and/or its associated membranous organelles. In fact, replication of...

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PMID: 26053926
DOI: 10.3390/v7062749

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