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Article

Exome Sequencing and Epigenetic Analysis of Twins Who Are Discordant for Congenital Cataract.

Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Aug 2015

Wei Tanwei, Sun Hui, Hu Bo, Yang Jie, Qiao Chen, Yan Ming

Abstract excerpt

PURPOSE: To further understand genetic factors that contribute to congenital cataracts, we sought to identify early post-twinning mutational and epigenetic events that may account for the discordant phenotypes of a twin pair. METHODS: A patient with a congenital cataract and her twin sister were assessed for genetic factors that might contribute to their discordant phenotypes by mutation screening of 11 candidate...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26045100
DOI: 10.1017/thg.2015.34

Genes

CRYAA
GJA3
HSF4
TRAM1
VEGFA
CADPS
CRYAB
CRYBA1
CRYBB1
CRYBB2
CRYGC
CRYGD
DCT
FRYL
FTL
GJA8
GSR
MIP
NARS2
PLEKHO2
RBP3
TEKT4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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