Article
GLU298ASP and 4G/5G Polymorphisms and the Risk of Ischemic Stroke in Young Individuals.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques - 1 Sept 2015
Esparza-García Juan Carlos, Santiago-Germán David, Guadalupe Valades-Mejía María, Hernández-Juárez Jesus, Aguilar-Sosa Eberth, Leaños-Miranda Alfredo, Alvarado-Moreno Antonio, Majluf-Cruz Abraham, Isordia-Salas Irma
Abstract excerpt
BACKGROUND: Polymorphisms in the endothelial nitric oxide synthase (eNOS) and in the plasminogen activator inhibitor -1 (PAI-1) genes have been implicated in stroke pathogenesis but results are still controversial. The aim of this study was to examine the possible contribution of Glu298Asp in the eNOS and 4G/5G in the PAI-1polymorphisms with ischemic stroke in a young Mexican population. MATERIALS AND METHODS: In...
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