Article
Maternal PPARG Pro12Ala polymorphism is associated with infant's neurodevelopmental outcomes at 18 months of age.
Early human development - 1 Aug 2015
Torres-Espínola Francisco J, Altmäe Signe, Segura Maria Teresa, Jerez Antonio, Anjos Tania, Chisaguano Maribel, Carmen López-Sabater M, Entrala Carmen, Alvarez Juan Carlos, Agil Ahmad, Florido Jesus, Catena Andres, Pérez-García Miguel, Campoy Cristina
Abstract excerpt
BACKGROUND: Peroxisome proliferator activated receptors (PPARs) are ligand activated transcription factors with crucial functions in lipid homeostasis, glucose metabolism, anti-inflammatory processes, placental development, and are involved in cognitive functions and neurodegenerative diseases. Polymorphisms in PPAR genes are shown to influence the activity of these receptors. AIMS: 1) To examine the association...
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