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Article

Assumption-free estimation of the genetic contribution to refractive error across childhood.

Molecular vision - 1 Jan 2015

Guggenheim Jeremy A, St Pourcain Beate, McMahon George, Timpson Nicholas J, Evans David M, Williams Cathy

Abstract excerpt

PURPOSE: Studies in relatives have generally yielded high heritability estimates for refractive error: twins 75-90%, families 15-70%. However, because related individuals often share a common environment, these estimates are inflated (via misallocation of unique/common environment variance). We calculated a lower-bound heritability estimate for refractive error free from such bias. METHODS: Between the ages 7 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26019481
PMCID: PMC4445077

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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