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Article

Myopia is predominantly genetic or predominantly environmental?

3 Mar 2025

Abstract excerpt

Jeremy A. Guggenheim High-prevalence diseases are generally attributed to a combination of genetic susceptibility and exposure to lifestyle-related risk factors. In the case of myopia, at each end of this multifactorial aetiology spectrum are examples with a purely genetic or purely environmental origin. Pedigrees carrying rare, highly penetrant disease-causing mutations can cause myopia irrespective of lifestyle...

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PMID: 40028922
DOI: 10.1111/opo.13464

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