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Article

KIT D816V and JAK2 V617F mutations are seen recurrently in hypereosinophilia of unknown significance.

American journal of hematology - 1 Sept 2015

Schwaab Juliana, Umbach Roland, Metzgeroth Georgia, Naumann Nicole, Jawhar Mohamad, Sotlar Karl, Horny Hans-Peter, Gaiser Timo, Hofmann Wolf-Karsten, Schnittger Susanne, Cross Nicholas C P, Fabarius Alice, Reiter Andreas

Abstract excerpt

Myeloproliferative neoplasms with eosinophilia are commonly characterized by a normal karyotype and remain poorly defined at the molecular level. We therefore investigated 426 samples from patients with hypereosinophilia of unknown significance initially referred for screening of the FIP1L1-PDGFR...

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Source

Identifiers

PMID: 26017288
DOI: 10.1002/ajh.24075

Genes

KIT
JAK2
PDGFRA
SRSF2
TET2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26017288-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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