Article
The CASC15 Long Intergenic Noncoding RNA Locus Is Involved in Melanoma Progression and Phenotype Switching.
The Journal of investigative dermatology - 1 Oct 2015
Lessard Laurent, Liu Michelle, Marzese Diego M, Wang Hongwei, Chong Kelly, Kawas Neal, Donovan Nicholas C, Kiyohara Eiji, Hsu Sandy, Nelson Nellie, Izraely Sivan, Sagi-Assif Orit, Witz Isaac P, Ma Xiao-Jun, Luo Yuling, Hoon Dave S B
Abstract excerpt
In recent years, considerable advances have been made in the characterization of protein-coding alterations involved in the pathogenesis of melanoma. However, despite their growing implication in cancer, little is known about the role of long noncoding RNAs in melanoma progression. We hypothesized that copy number alterations (CNAs) of intergenic nonprotein-coding domains could help identify long intergenic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.