Article
Novel MHC class I full-length allele and haplotype characterization in sooty mangabeys.
Immunogenetics - 1 Aug 2015
Heimbruch Katelyn E, Karl Julie A, Wiseman Roger W, Dudley Dawn M, Johnson Zach, Kaur Amitinder, O'Connor David H
Abstract excerpt
Sooty mangabeys (Cercocebus atys) are natural SIV hosts and the presumed source of HIV-2 and SIVmac, which makes them a valuable model for HIV/SIV research. However, like other African primates, little is known about their major histocompatibility complex (MHC) genetics. In this study, we used Roche/454 and Illumina MiSeq deep sequencing in order to determine the MHC class I transcripts in a cohort of 165 sooty...
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