Article
Variants in ELL2 influencing immunoglobulin levels associate with multiple myeloma.
Nature communications - 26 May 2015
Swaminathan Bhairavi, Thorleifsson Guðmar, Jöud Magnus, Ali Mina, Johnsson Ellinor, Ajore Ram, Sulem Patrick, Halvarsson Britt-Marie, Eyjolfsson Guðmundur, Haraldsdottir Vilhelmina, Hultman Christina, Ingelsson Erik, Kristinsson Sigurður Y, Kähler Anna K, Lenhoff Stig, Masson Gisli, Mellqvist Ulf-Henrik, Månsson Robert, Nelander Sven, Olafsson Isleifur, Sigurðardottir Olof, Steingrimsdóttir Hlif, Vangsted Annette, Vogel Ulla, Waage Anders, Nahi Hareth, Gudbjartsson Daniel F, Rafnar Thorunn, Turesson Ingemar, Gullberg Urban, Stefánsson Kári, Hansson Markus, Thorsteinsdóttir Unnur, Nilsson Björn
Abstract excerpt
Multiple myeloma (MM) is characterized by an uninhibited, clonal growth of plasma cells. While first-degree relatives of patients with MM show an increased risk of MM, the genetic basis of inherited MM susceptibility is incompletely understood. Here we report a genome-wide association study in th...
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