Article
Polymorphisms in C-reactive protein and Glypican-5 are associated with lung cancer risk and Gartrokine-1 influences Cisplatin-based chemotherapy response in a Chinese Han population.
Disease markers - 1 Jan 2015
Zhang Shuo, Thakur Asmitananda, Liang Yiqian, Wang Ting, Gao Lei, Yang Tian, Li Yang, Geng Tingting, Jin Tianbo, Chen Tianjun, Liu Johnson J, Chen Mingwei
Abstract excerpt
The role of genetics in progression of cancer is an established fact, and susceptibility risk and difference in outcome to chemotherapy may be caused by the variation in low-penetrance alleles of risk genes. We selected seven genes (CRP, GPC5, ACTA2, AGPHD1, SEC14L5, RBMS3, and GKN1) that previously reported link to lung cancer (LC) and genotyped single nucleotide polymorphisms (SNPs) of these genes in a...
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