Article
Association Between TRAF6 Gene Polymorphisms and Susceptibility of Ischemic Stroke in Southern Chinese Han Population.
Journal of molecular neuroscience : MN - 1 Nov 2015
Su Li, Chen Ziwen, Yan Yan, Liang Baoyun, Xie Juanjuan, Chen Qing, Tan Jinjing, Gu Lian
Abstract excerpt
The tumor necrosis factor receptor-associated factor 6 (TRAF6) gene encodes a protein that acts downstream of the Toll-like receptor (TLR) pathway. TLRs activate inflammatory cascades and mediate inflammatory injury after cerebral ischemia. However, the role of TFAR6 gene polymorphisms in ischemic stroke (IS) remains unknown. This study aims to investigate the associations of TRAF6 gene polymorphisms with...
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