Article
The role of CGRP and CALCA T-692C single-nucleotide polymorphism in psoriasis vulgaris.
Die Pharmazie - 1 Feb 2015
Guo Ren, Li Fang-Fang, Chen Ming-Liang, Ya Ming-Zhu, He Hui-Lan, Li Dai
Abstract excerpt
Calcitonin gene related protein (CGRP) is increased in both lesional and non-lesional psoriasis. The role of CGRP in the pathogenesis of psoriasis vulgaris is still not clear. We designed to determine the CGRP-I (or CALCA), II (or CALCB) gene expression and morbidity and CALCA T-692C single-nucleotide polymorphism (SNP). Peripheral blood mononuclear cells (PBMCs) and plasma samples were collected, and CGRP level...
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