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Article

Regulated nucleocytoplasmic transport in spermatogenesis: a driver of cellular differentiation?

1 Jan 2005

Abstract excerpt

This review explores the hypothesis that regulation of nucleocytoplasmic shuttling is a means of driving differentiation, using spermatogenesis as a model. The transition from undifferentiated spermatogonial stem cell to terminally differentiated spermatozoon is, at its most basic, a change in the repertoire of expressed genes. To effect this, the complement of nuclear proteins, such as transcription factors and...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 16163727
DOI: 10.1002/bies.20289

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