Short report: Monitoring ESR1 mutations by circulating tumor DNA in aromatase inhibitor resistant metastatic breast cancer.

doi:10.1002/ijc.29612

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Short report: Monitoring ESR1 mutations by circulating tumor DNA in aromatase inhibitor resistant metastatic breast cancer.

International journal of cancer - 15 Nov 2015

Sefrioui David, Perdrix Anne, Sarafan-Vasseur Nasrin, Dolfus Claire, Dujon Antoine, Picquenot Jean-Michel, Delacour Julien, Cornic Marie, Bohers Elodie, Leheurteur Marianne, Rigal Olivier, Tennevet Isabelle, Thery Jean-Christophe, Alexandru Cristina, Guillemet Cécile, Moldovan Cristian, Veyret Corinne, Frebourg Thierry, Di Fiore Frédéric, Clatot Florian

Abstract excerpt

Acquired estrogen receptor gene (ESR1) mutations have been recently reported as a marker of resistance to aromatase inhibitors in hormone receptor positive metastatic breast cancer. We retrospectively considered seven patients treated for metastatic breast cancer with available samples from the primary tumor before any treatment, cryopreserved metastasis removed during progression and concomitant plasmas. All...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 25994408
DOI: 10.1002/ijc.29612

Genes

ESR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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