Article
Gene-expression profiles correlate with the efficacy of anti-EGFR therapy and chemotherapy for colorectal cancer.
International journal of clinical oncology - 1 Dec 2015
Inoue Masahiro, Takahashi Shin, Soeda Hiroshi, Shimodaira Hideki, Watanabe Mika, Miura Koh, Sasaki Iwao, Kato Shunsuke, Ishioka Chikashi
Abstract excerpt
BACKGROUND: Comprehensive gene-expression analysis is very useful for classifying specific cancers into subgroups on the basis of their biological characteristics; it is used both prognostically and predictively. The purpose of this study was to classify unresectable advanced or recurrent colorectal cancer (CRC) by gene-expression profiling of formalin-fixed paraffin-embedded tissues and to correlate CRC...
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