Article
The application of genome editing in studying hearing loss.
Hearing research - 1 Sept 2015
Zou Bing, Mittal Rahul, Grati M'hamed, Lu Zhongmin, Shu Yilai, Tao Yong, Feng Youg, Xie Dinghua, Kong Weijia, Yang Shiming, Chen Zheng-Yi, Liu Xuezhong
Abstract excerpt
Targeted genome editing mediated by clustered, regularly interspaced, short palindromic repeat (CRISPR)/CRISPR-associated nuclease 9 (Cas9) technology has emerged as one of the most powerful tools to study gene functions, and with potential to treat genetic disorders. Hearing loss is one of the most common sensory disorders, affecting approximately 1 in 500 newborns with no treatment. Mutations of inner ear genes...
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