NLRP7 in the spectrum of reproductive wastage: rare non-synonymous variants confer genetic susceptibility to recurrent reproductive wastage.

doi:10.1136/jmg.2011.089144

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

NLRP7 in the spectrum of reproductive wastage: rare non-synonymous variants confer genetic susceptibility to recurrent reproductive wastage.

Journal of medical genetics - 1 Aug 2011

Messaed Christiane, Chebaro Wafaa, Di Roberto Raphael B, Rittore Cecile, Cheung Annie, Arseneau Jocelyne, Schneider Ariel, Chen Moy Fong, Bernishke Kurt, Surti Urvashi, Hoffner Lori, Sauthier Philippe, Buckett William, Qian JianHua, Lau Nga Man, Bagga Rashmi, Engert James C, Coullin Philippe, Touitou Isabelle, Slim Rima

Abstract excerpt

BACKGROUND: NLRP7 mutations are responsible for recurrent molar pregnancies and associated reproductive wastage. To investigate the role of NLRP7 in sporadic moles and other forms of reproductive wastage, the authors sequenced this gene in a cohort of 135 patients with at least one hydatidiform mole or three spontaneous abortions; 115 of these were new patients. METHODS/RESULTS: All mutations were reviewed and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Habitual

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Abortion, Spontaneous

Share to Hydatidiform Mole

Share to Interleukin-1beta

Share to Leukocytes, Mononuclear

Share to Mutant Proteins

Share to Placenta

Share to Reproduction

Source

Open in PubMed

Identifiers

PMID: 21659348
DOI: 10.1136/jmg.2011.089144

Genes

NLRP7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

NLRP7 in the spectrum of reproductive wastage: rare non-synonymous variants confer genetic susceptibility to recurrent reproductive wastage.PMID 21659348Read ↗

Novel NLRP7 mutations in familial recurrent hydatidiform mole: are NLRP7 mutations a risk for recurrent reproductive wastage?Semantic proximity Read ↗

Maternal NLRP7 and C6orf221 variants are not a common risk factor for androgenetic moles, triploidy and recurrent miscarriage.Semantic proximity Read ↗

The genetics of recurrent hydatidiform moles in China: correlations between NLRP7 mutations, molar genotypes and reproductive outcomes.Semantic proximity Read ↗

Identification of 13 novel NLRP7 mutations in 20 families with recurrent hydatidiform mole; missense mutations cluster in the leucine-rich region.Semantic proximity Read ↗

Mutations in NLRP7 are associated with diploid biparental hydatidiform moles, but not androgenetic complete moles.Semantic proximity Read ↗

Recurrent hydatidiform mole: detection of two novel mutations in the NLRP7 gene in two Egyptian families.Semantic proximity Read ↗

The p.L750V mutation in the NLRP7 gene is frequent in Mexican patients with recurrent molar pregnancies and is not associated with recurrent pregnancy loss.Semantic proximity Read ↗

Women heterozygous for NALP7/NLRP7 mutations are at risk for reproductive wastage: report of two novel mutations.Semantic proximity Read ↗

A Novel Mutation in NLRP7 Related to Recurrent Hydatidiform Mole and Reproductive Failure.Semantic proximity Read ↗

The genetics of recurrent hydatidiform moles in Mexico: further evidence of a strong founder effect for one mutation in NLRP7 and its widespread.Semantic proximity Read ↗

Recurrent pregnancy loss in a woman with NLRP7 mutation: not all molar pregnancies can be easily classified as either "partial" or "complete" hydatidiform moles.Semantic proximity Read ↗

Biallelic NLRP7 variants in patients with recurrent hydatidiform mole: A review and expert consensus.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.