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Clostridium sordellii genome analysis reveals plasmid localized toxin genes encoded within pathogenicity loci

15 May 2015

Abstract excerpt

BACKGROUND: Clostridium sordellii can cause severe infections in animals and humans, the latter associated with trauma, toxic shock and often-fatal gynaecological infections. Strains can produce two large clostridial cytotoxins (LCCs), TcsL and TcsH, related to those produced by Clostridium difficile, Clostridium novyi and Clostridium perfringens, but the genetic basis of toxin production remains uncharacterised....

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PMID: 25981746
DOI: 10.1186/s12864-015-1613-2

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