Article
Phase II study of biomarker-guided neoadjuvant treatment strategy for IIIA-N2 non-small cell lung cancer based on epidermal growth factor receptor mutation status.
Journal of hematology & oncology - 17 May 2015
Zhong Wenzhao, Yang Xuening, Yan Honghong, Zhang Xuchao, Su Jian, Chen Zhihong, Liao Riqiang, Nie Qiang, Dong Song, Zhou Qing, Yang Jinji, Tu Haiyan, Wu Yi-Long
Abstract excerpt
BACKGROUND: Neoadjuvant erlotinib and customized adjuvant therapy are appealing but controversial. The purpose of this study was to evaluate the role of biomarker-guided neoadjuvant treatment strategy in patients with IIIA-N2 non-small cell lung cancer (NSCLC) stratified by epidermal growth factor receptor (EGFR) mutation status. FINDINGS: Patients with resectable histologically documented stage IIIA-N2 NSCLC...
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