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Article

Ullrich-Turner Syndrome and Tumor Risk: Is There Another Chance to Early Gonadectomy in Positive TSPY and SRY Patients?

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie - 1 Jun 2016

Silveri Massimiliano, Grossi Armando, Bassani Francesca, Orazi Cinzia, Camassei Francesca Diomedi, Zaccara Antonio

Abstract excerpt

The presence of the Y chromosome in the karyotype of patients with disorders of sex differentiation is significantly associated with an increased risk to develop specific types of malignancies, predominantly type II germ cell tumors (GCTs). Gonadoblastoma in the gonads without an obvious testicular differentiation and intratubular germ cell neoplasia of unclassified type in testicular tissue are the precursor...

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Share to Cell Cycle Proteins
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25978024
DOI: 10.1055/s-0035-1551568

Genes

SRY

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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Ullrich-Turner Syndrome and Tumor Risk: Is There Another Chance to Early Gonadectomy in Positive TSPY and SRY Patients?PMID 25978024Read ↗

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Gonadoblastoma in Turner syndrome and Y‐chromosome‐derived materialSemantic proximity Read ↗

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New insights into type II germ cell tumor pathogenesis based on studies of patients with various forms of disorders of sex development (DSD).Semantic proximity Read ↗

Tumor Risk in Disorders of Sex DevelopmentSemantic proximity Read ↗

Predicting Gonadal Germ Cell Cancer in People with Disorders of Sex Development; Insights from Developmental Biology.Semantic proximity Read ↗

OCT4 immunohistochemistry may be necessary to identify the real risk of gonadal tumors in patients with Turner syndrome and Y chromosome sequencesSemantic proximity Read ↗

SRY Gene Increases the Risk of Developing Gonadoblastoma and/or Nontumoral Gonadal Lesions in Turner SyndromeSemantic proximity Read ↗

SRY Mutation and Tumor Formation on the Gonads of XY Pure Gonadal Dysgenesis PatientsSemantic proximity Read ↗

Gonadal Development and Tumor Formation at the Crossroads of Male and Female Sex DeterminationSemantic proximity Read ↗

Increased risk of gonadal malignancy and prophylactic gonadectomy: a study of 102 phenotypic female patients with Y chromosome or Y-derived sequences.Semantic proximity Read ↗

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