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Article

Increased risk of gonadal malignancy and prophylactic gonadectomy: a study of 102 phenotypic female patients with Y chromosome or Y-derived sequences.

Human reproduction (Oxford, England) - 1 Jul 2014

Liu Ai-Xia, Shi Hai-Yan, Cai Zhe-Jun, Liu Aiping, Zhang Dan, Huang He-Feng, Jin Hang-Mei

Abstract excerpt

STUDY QUESTION: What is the optimal protocol of management for phenotypic female patients with Y chromosome or Y-derived sequences, in particular for adult patients? SUMMARY ANSWER: Immediate gonadectomy, long-term hormone therapy and psychological care are suggested to be the optimal management for older phenotypic female patients with Y chromosome or Y-derived sequences. WHAT IS KNOWN ALREADY: Phenotypic female...

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Source

Identifiers

PMID: 24826988
DOI: 10.1093/humrep/deu109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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