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Article

[Study of negative feedback between wild-type BRAF or RAFV600E and Mps1 in melanoma].

Zhonghua bing li xue za zhi = Chinese journal of pathology - 1 Apr 2015

Zhang Ling, He Chanting, Bi Yanghui, Liu Feng, Cui Heyang, Wang Juan, Song Bin, Shi Ruyi, Yang Bin, Wang Fang, Jia Zhiwu, Zhao Zhenxiang, Liu Jing

Abstract excerpt

OBJECTIVE: To study the effect of Mps1 on BRAFWT/MEK/ERK pathway in the presence of wild type BRAF or BRAFV600E in melanoma. METHODS: Melanoma cells harboring BRAFWT genotype were transfected either with pBabe-puro-GST-BRAF-WT and/or pBabe-puro-GFP-Mps1-WT or pBabe-puro-GST-BRAFV600E and/or pBabe...

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Source

Identifiers

PMID: 25975913

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25975913-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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