Article
Adding Erlotinib to Chemoradiation Improves Overall Survival but Not Progression-Free Survival in Stage III Non-Small Cell Lung Cancer.
International journal of radiation oncology, biology, physics - 1 Jun 2015
Komaki Ritsuko, Allen Pamela K, Wei Xiong, Blumenschein George R, Tang Ximing, Lee J Jack, Welsh James W, Wistuba Ignacio I, Liu Diane D, Hong Waun Ki
Abstract excerpt
PURPOSE: To test, in a single-arm, prospective, phase 2 trial, whether adding the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor erlotinib to concurrent chemoradiotherapy for previously untreated, locally advanced, inoperable non-small cell lung cancer would improve survival and disease control without increasing toxicity. METHODS AND MATERIALS: Forty-eight patients with previously untreated...
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