Article
Management of medically inoperable and tyrosine kinase inhibitor-naïve early-stage lung adenocarcinoma with epidermal growth factor receptor mutations: a retrospective multi-institutional analysis.
BMC cancer - 13 Jul 2020
Sun Yuemei, Wu Mengwan, Zhou Mingxiu, Luo Xing, Guo Yan, Bai Hansong, Zhang Zican, Tian Wei, Wang Xiaoshan, Bai Yifeng, Zhu Xueqiang, Pan Haixia, Deng Ying, Hu Honglin, Xia Jianling, Hao Xinbao, Han Liangfu, Wei Min, Liu Yingyi, Zeng Ming
Abstract excerpt
BACKGROUND: The clinical value of combined local radiation and epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) for medically inoperable and TKI-naïve early-stage lung adenocarcinoma patients with EGFR mutations has not yet been determined. In this study, we aimed to pool multi-institutional data to compare the therapeutic effect of EGFR-TKI treatment alone and combined radiation and TKI...
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