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Article

Single-agent gefitinib with concurrent radiotherapy for locally advanced non-small cell lung cancer harboring mutations of the epidermal growth factor receptor.

Lung cancer (Amsterdam, Netherlands) - 1 May 2011

Okamoto Isamu, Takahashi Toshiaki, Okamoto Hiroaki, Nakagawa Kazuhiko, Watanabe Koshiro, Nakamatsu Kiyoshi, Nishimura Yasumasa, Fukuoka Masahiro, Yamamoto Nobuyuki

Abstract excerpt

INTRODUCTION: A feasibility study was performed to examine the safety and toxicity profile of daily gefitinib (250 mg) administration with concurrent definitive thoracic radiation therapy (TRT) in patients with unresectable non-small cell lung cancer (NSCLC) of stage III. METHODS: Patients received a 14-day induction therapy with gefitinib at 250 mg daily. TRT was initiated on day 15 in 2-Gy fractions...

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Identifiers

PMID: 20828860
DOI: 10.1016/j.lungcan.2010.08.016

Genes

EGFR

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Source receipt: pubmed, retrieved 7 Sept 2026.

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