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Article

Efficacy and safety of EGFR inhibitors and radiotherapy in locally advanced non-small-cell lung cancer: a meta-analysis.

Future oncology (London, England) - 1 Sept 2022

Li Xue, Wang Fang, Jia Huijun, Lian Zhen, Ren Kai, Yuan Zhiyong, Wang Ping, Zhao Lujun

Abstract excerpt

Aim: To assess the efficacy and safety of EGFR inhibitors combined with (chemo)radiotherapy in unresectable, locally advanced non-small-cell lung cancer. Materials & methods: A systematic review and meta-analysis of prospective trials was performed. Results: Twenty-eight studies of 1640 patients were included. In patients harboring EGFR-sensitive mutations, the pooled objective response rate, 1-year overall...

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PMID: 35947522
DOI: 10.2217/fon-2022-0491

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