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A Novel Gene Inactivation System Reveals Altered Periplasmic Flagellar Orientation in aBorrelia burgdorferi fliLMutant

27 Mar 2011

Abstract excerpt

Motility and chemotaxis are essential components of pathogenesis for many infectious bacteria, including Borrelia burgdorferi, the causative agent of Lyme disease. Motility and chemotaxis genes comprise 5 to 6% of the genome of B. burgdorferi, yet the functions of most of those genes remain uncharacterized, mainly due to the paucity of a nonpolar gene inactivation system. In this communication, we describe the...

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PMID: 21441522
DOI: 10.1128/jb.00202-11

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