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Article

A Human Thrifty Phenotype Associated With Less Weight Loss During Caloric Restriction.

Diabetes - 1 Aug 2015

Reinhardt Martin, Thearle Marie S, Ibrahim Mostafa, Hohenadel Maximilian G, Bogardus Clifton, Krakoff Jonathan, Votruba Susanne B

Abstract excerpt

Successful weight loss is variable for reasons not fully elucidated. Whether effective weight loss results from smaller reductions in energy expenditure during caloric restriction is not known. We analyzed whether obese individuals with a "thrifty" phenotype, that is, greater reductions in 24-h energy expenditure during fasting and smaller increases with overfeeding, lose less weight during caloric restriction...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25964395
DOI: 10.2337/db14-1881
PMCID: PMC4512223

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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