Article
FGF signaling supports Drosophila fertility by regulating development of ovarian muscle tissues.
Developmental biology - 1 Aug 2015
Irizarry Jihyun, Stathopoulos Angelike
Abstract excerpt
The thisbe (ths) gene encodes a Drosophila fibroblast growth factor (FGF), and mutant females are viable but sterile suggesting a link between FGF signaling and fertility. Ovaries exhibit abnormal morphology including lack of epithelial sheaths and muscle tissues that surround ovarioles. Here we investigated how FGF influences Drosophila ovary morphogenesis and identified several roles. Heartless (Htl) FGF...
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