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Fibroblast growth factor signaling is required for early somatic gonad development in zebrafish

5 Sept 2017

Abstract excerpt

The vertebrate ovary and testis develop from a sexually indifferent gonad. During early development of the organism, primordial germ cells (the gamete lineage) and somatic gonad cells coalesce and begin to undergo growth and morphogenesis to form this bipotential gonad. Although this aspect of development is requisite for a fertile adult, little is known about the genetic regulation of early gonadogenesis in any...

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PMID: 28873404
DOI: 10.1371/journal.pgen.1006993

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