Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype.

Arthritis research & therapy - 7 May 2015

FitzGerald Oliver, Haroon Muhammad, Giles Jon T, Winchester Robert

Abstract excerpt

This review focuses on the genetic features of psoriatic arthritis (PsA) and their relationship to phenotypic heterogeneity in the disease, and addresses three questions: what do the recent studies on human leukocyte antigen (HLA) tell us about the genetic relationship between cutaneous psoriasis (PsO) and PsA - that is, is PsO a unitary phenotype; is PsA a genetically heterogeneous or homogeneous entity; and do...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Arthritis, Psoriatic
Share to Gene Expression Regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genotype

Share to HLA Antigens

Share to Prognosis

Share to Severity of Illness Index

Source

Open in PubMed Open full text

Identifiers

PMID: 25948071
DOI: 10.1186/s13075-015-0640-3
PMCID: PMC4422545

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Concepts of pathogenesis in psoriatic arthritis: genotype determines clinical phenotype.PMID 25948071Read ↗

Certain class I HLA alleles and haplotypes implicated in susceptibility play a role in determining specific features of the psoriatic arthritis phenotype.Semantic proximity Read ↗

Clinical and immunogenetic characterization in psoriatic arthritis patients.Semantic proximity Read ↗

New developments in our understanding of psoriatic arthritis and their impact on the diagnosis and clinical management of the disease.Semantic proximity Read ↗

HLA associations reveal genetic heterogeneity in psoriatic arthritis and in the psoriasis phenotype.Semantic proximity Read ↗

What have we learned about genetic susceptibility in psoriasis and psoriatic arthritis?Semantic proximity Read ↗

Clinical and molecular significance of genetic loci associated with psoriatic arthritis.Semantic proximity Read ↗

The many faces of psoriatic arthritis: their genetic determinism.Semantic proximity Read ↗

Psoriatic arthritis: genetics and pathogenesis.Semantic proximity Read ↗

Implications of the diversity of class I HLA associations in psoriatic arthritis.Semantic proximity Read ↗

Genetic Studies Investigating Susceptibility to Psoriatic Arthritis: A Narrative Review.Semantic proximity Read ↗

Psoriatic arthritis: from pathogenesis to therapy.Semantic proximity Read ↗

Genetic epidemiology of psoriasis and psoriatic arthritis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.