Article
Certain class I HLA alleles and haplotypes implicated in susceptibility play a role in determining specific features of the psoriatic arthritis phenotype.
Annals of the rheumatic diseases - 1 Jan 2016
Haroon Muhammad, Winchester Robert, Giles Jon T, Heffernan Eric, FitzGerald Oliver
Abstract excerpt
OBJECTIVES: Psoriatic arthritis (PsA) susceptibility is associated with several different class I alleles, suggesting separate patterns of MHC effect. This exploratory study was based on the hypothesis that heterogeneity of the clinical phenotype of PsA might be explained by differing associations of clinical features with these susceptibility genes. METHODS: The clinical phenotype of 282 PsA patients in a cohort...
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