Article
Genomic profile of a Li-Fraumeni-like syndrome patient with a 45,X/46,XX karyotype, presenting neither mutations in TP53 nor clinical stigmata of Turner syndrome.
Cancer genetics - 1 Jun 2015
Basso Tatiane R, Villacis Rolando A R, Canto Luisa M, Alves Vinicius M F, Lapa Rainer M L, Nóbrega Amanda F, Achatz Maria I, Rogatto Silvia R
Abstract excerpt
Li-Fraumeni syndrome (LFS) is a hereditary disorder that predisposes patients to several types of cancer and is associated with TP53 germline mutations. Turner syndrome (TS) is one of the most common aneuploidies in women. Patients with TS have a higher risk of developing cancer, although multipl...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.