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MLVA-typing on Streptococcus pneumoniae serotype 1 isolated from meningitis cases in Niger before the introduction of PCV-13 revealed a low genetic diversity.

Transactions of the Royal Society of Tropical Medicine and Hygiene - 1 Jul 2015

Alio Sanda Abdelkader, Granger Farbos Alexandra, Hamidou Amina Amadou, Vonaesch Pascale, Jusot Jean-François, Koeck Jean-Louis, Collard Jean-Marc

Abstract excerpt

BACKGROUND: Serotype 1 was the most prevalent pneumococcal meningitis serotype encountered in Niger over the period 2003-2011 (pre-vaccination era), accounting for 45.3% of infections. METHODS: Multiple locus VNTR analysis (MLVA) was used to create a genotypic snapshot of a representative subset of the pneumococcal population of serotype 1. RESULTS: MLVA using 16 markers revealed a homogeneous genetic background...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 25934981
DOI: 10.1093/trstmh/trv033

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