Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Abnormal FISH in patients with immunoglobulin light chain amyloidosis is a risk factor for cardiac involvement and for death

1 May 2015

Abstract excerpt

Importance of interphase fluorescent in situ hybridization (FISH) with cytoplasmic staining of immunoglobulin FISH (cIg-FISH) on bone marrow is not well understood in light chain amyloidosis (AL). This is in contrast with multiple myeloma where prognostic and treatment related decisions are dependent on cytogenetic testing. This retrospective study reviewed 401 AL patients with cIg-FISH testing performed at our...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloidosis: Diagnosis, Treatment, Outcomes
Share to Multiple Myeloma Research and Treatments
Share to Protein Kinase Regulation and GTPase Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25933374
DOI: 10.1038/bcj.2015.34

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Abnormal FISH in patients with immunoglobulin light chain amyloidosis is a risk factor for cardiac involvement and for deathPMID 25933374Read ↗

Translocation t(11;14) and survival of patients with light chain (AL) amyloidosisSemantic proximity Read ↗

AL amyloidosis: The effect of fluorescent in situ hybridization abnormalities on organ involvement and survivalSemantic proximity Read ↗

Evaluation of the cytogenetic aberration pattern in amyloid light chain amyloidosis as compared with monoclonal gammopathy of undetermined significance reveals common pathways of karyotypic instabilitySemantic proximity Read ↗

Translocations involving the immunoglobulin heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosisSemantic proximity Read ↗

Translocations of 14q32 and deletions of 13q14 are common chromosomal abnormalities in systemic amyloidosisSemantic proximity Read ↗

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis.Semantic proximity Read ↗

Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myelomaSemantic proximity Read ↗

Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14)Semantic proximity Read ↗

Biomarkers in AL AmyloidosisSemantic proximity Read ↗

Chromosomal abnormalities in systemic amyloidosisSemantic proximity Read ↗

Functional Subsets of Plasma Cells Associated with Amyloid Production and Venetoclax Sensitivity in Light Chain AmyloidosisSemantic proximity Read ↗

Epidemiology of Systemic Light-Chain (AL) AmyloidosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.