Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Translocation t(11;14) and survival of patients with light chain (AL) amyloidosis

11 Feb 2009

Abstract excerpt

BACKGROUND: Light chain amyloidosis is a rare plasma cell dyscrasia. Interphase fluorescence in situ hybridization (FISH) coupled to cytoplasmic staining of specific Ig (cIg-FISH) on bone marrow plasma cells has become well established in the initial evaluation of multiple myeloma, a related disorder. Little, however, is known about cytogenetic abnormalities in patients with light chain amyloidosis. DESIGN AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyloidosis: Diagnosis, Treatment, Outcomes
Share to Chronic Lymphocytic Leukemia Research
Share to Protein Kinase Regulation and GTPase Signaling

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19211640
DOI: 10.3324/haematol.13369

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Translocation t(11;14) and survival of patients with light chain (AL) amyloidosisPMID 19211640Read ↗

Abnormal FISH in patients with immunoglobulin light chain amyloidosis is a risk factor for cardiac involvement and for deathSemantic proximity Read ↗

Evaluation of the cytogenetic aberration pattern in amyloid light chain amyloidosis as compared with monoclonal gammopathy of undetermined significance reveals common pathways of karyotypic instabilitySemantic proximity Read ↗

Translocations involving the immunoglobulin heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosisSemantic proximity Read ↗

Translocations of 14q32 and deletions of 13q14 are common chromosomal abnormalities in systemic amyloidosisSemantic proximity Read ↗

AL amyloidosis: The effect of fluorescent in situ hybridization abnormalities on organ involvement and survivalSemantic proximity Read ↗

Cytogenetic intraclonal heterogeneity of plasma cell dyscrasia in AL amyloidosis as compared with multiple myelomaSemantic proximity Read ↗

Novel recurrent chromosomal aberrations detected in clonal plasma cells of light chain amyloidosis patients show potential adverse prognostic effect: first results from a genome-wide copy number array analysis.Semantic proximity Read ↗

Hyperdiploidy is less frequent in AL amyloidosis compared with monoclonal gammopathy of undetermined significance and inversely associated with translocation t(11;14)Semantic proximity Read ↗

Chromosomal abnormalities in systemic amyloidosisSemantic proximity Read ↗

Primary extramedullary plasmacytoma: similarities with and differences from multiple myeloma revealed by interphase cytogeneticsSemantic proximity Read ↗

Multiple myeloma involving central nervous system: high frequency of chromosome 17p13.1 (p53) deletionsSemantic proximity Read ↗

Deletion of chromosome band 13q14 as detected by fluorescence in situ hybridization is a prognostic factor in patients with multiple myeloma who are receiving allogeneic dose-reduced stem cell transplantationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.