Article
Allelic Diversity and Geographical Distribution of the Gene Encoding Plasmodium falciparum Merozoite Surface Protein-3 in Thailand.
The Korean journal of parasitology - 1 Apr 2015
Sawaswong Vorthon, Simpalipan Phumin, Siripoon Napaporn, Harnyuttanakorn Pongchai, Pattaradilokrat Sittiporn
Abstract excerpt
Merozoite surface proteins (MSPs) of malaria parasites play critical roles during the erythrocyte invasion and so are potential candidates for malaria vaccine development. However, because MSPs are often under strong immune selection, they can exhibit extensive genetic diversity. The gene encoding the merozoite surface protein-3 (MSP-3) of Plasmodium falciparum displays 2 allelic types, K1 and 3D7. In Thailand,...
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