Article
Differential selective pressures on the merozoite surface protein 2 locus of Plasmodium falciparum in a low endemic area.
Gene - 31 Dec 2008
Putaporntip Chaturong, Jongwutiwes Somchai, Hughes Austin L
Abstract excerpt
195 Plasmodium falciparum merozoite surface protein-2 alleles collected in Tak Province, Thailand, in 1996 and 2006 revealed extremely limited sequence polymorphism except in the variable (V) region, which defines the two allelic families 3D7 and FC27. This pattern is most easily explained by repeated inter-allelic gene conversion events homogenizing alleles outside the V region. Comparison of synonymous and...
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