Article
Distinct serum metabolomics profiles associated with malignant progression in the KrasG12D mouse model of pancreatic ductal adenocarcinoma.
BMC genomics - 1 Jan 2015
LaConti Joseph J, Laiakis Evagelia C, Mays Anne Deslattes, Peran Ivana, Kim Sung Eun, Shay Jerry W, Riegel Anna T, Fornace Albert J, Wellstein Anton
Abstract excerpt
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer deaths worldwide with less than a 6% 5-year survival rate. PDAC is associated with poor prognosis based on the late stage diagnosis of the disease. Current diagnostic tests lack the sensitivity and specifici...
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