Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Fumarate Hydratase Mutation in a Young Woman With Uterine Leiomyomas and a Family History of Renal Cell Cancer.

Obstetrics and gynecology - 1 Jul 2015

Mann Merry Lynn, Ezzati Mohammad, Tarnawa Edward D, Carr Bruce R

Abstract excerpt

BACKGROUND: Heterozygous gene mutations in fumarate hydratase can result in a syndrome characterized by hereditary (cutaneous and uterine) leiomyomatosis and renal cell cancer. This disorder has been described in more than 200 families, but the prevalence of the disease is unknown. CASE: A 22 year-old woman of Bangladeshi lineage presented with menorrhagia and pelvic pain secondary to uterine leiomyomas and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Renal Cell
Share to Codon, Nonsense
Share to Fumarate Hydratase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Markers

Share to Heterozygote

Share to Kidney Neoplasms

Share to Leiomyomatosis

Share to Uterine Neoplasms

Source

Identifiers

PMID: 25923021
DOI: 10.1097/AOG.0000000000000702

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Fumarate Hydratase Mutation in a Young Woman With Uterine Leiomyomas and a Family History of Renal Cell Cancer.PMID 25923021Read ↗

Hereditary Leiomyomatosis and Renal Cell Cancer.Semantic proximity Read ↗

The syndrome of hereditary leiomyomatosis and renal cell cancer (HLRCC): The clinical features of an individual with a fumarate hydratase gene mutation.Semantic proximity Read ↗

Strong family history of uterine leiomyomatosis warrants fumarate hydratase mutation screening.Semantic proximity Read ↗

A case report of hereditary leiomyomatosis and renal cell cancer.Semantic proximity Read ↗

Novel Fumarate Hydratase Mutation in Siblings With Early Onset Uterine Leiomyomas and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome.Semantic proximity Read ↗

The genetics of uterine leiomyomata: what clinicians need to know.Semantic proximity Read ↗

Association of Germline Mutations in the Fumarate Hydratase Gene and Uterine Fibroids in Women With Hereditary Leiomyomatosis and Renal Cell CancerSemantic proximity Read ↗

Clinical and molecular genetic aspects of hereditary multiple cutaneous leiomyomatosis.Semantic proximity Read ↗

Novel fumarate hydratase mutation in a family with atypical uterine leiomyomas and hereditary leiomyomatosis and renal cell cancer.Semantic proximity Read ↗

Germline Fumarate Hydratase Mutations in Families with Multiple Cutaneous and Uterine LeiomyomataSemantic proximity Read ↗

Fumarate hydratase gene mutation in two young patients with sporadic uterine fibroids.Semantic proximity Read ↗

A novel missense mutation in fumarate hydratase in an Italian patient with a diffuse variant of cutaneous leiomyomatosis (Reed's syndrome).Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.