Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The genetics of uterine leiomyomata: what clinicians need to know.

Obstetrics and gynecology - 1 Apr 2006

Stewart Elizabeth A, Morton Cynthia C

Abstract excerpt

The genetics of many complex diseases, including hypertension, diabetes, and asthma, are receiving intense investigation and beginning to have therapeutic relevance. Family medical history can be a critical source of information for providing optimal patient care. For gynecologists, knowledge of cancer susceptibility genes such as BRCA1 and BRCA2 and the genetic syndrome hereditary nonpolyposis colorectal cancer...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Regulation, Neoplastic
Share to HMGA2 Protein
Share to Incidence

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Leiomyoma

Share to Risk Assessment

Share to Sensitivity and Specificity

Share to Steroid 17-alpha-Hydroxylase

Share to Uterine Neoplasms

Source

Identifiers

PMID: 16582132
DOI: 10.1097/01.AOG.0000206161.84965.0b

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The genetics of uterine leiomyomata: what clinicians need to know.PMID 16582132Read ↗

Association of Germline Mutations in the Fumarate Hydratase Gene and Uterine Fibroids in Women With Hereditary Leiomyomatosis and Renal Cell CancerSemantic proximity Read ↗

Clinical and molecular genetic aspects of hereditary multiple cutaneous leiomyomatosis.Semantic proximity Read ↗

Implications of Fumarate Hydratase Deficiency (FHD) and Cancer Risk: A Window into the Clinical and Oncological Implications of a Rare Disorder in GynecologySemantic proximity Read ↗

Novel fumarate hydratase mutation in a family with atypical uterine leiomyomas and hereditary leiomyomatosis and renal cell cancer.Semantic proximity Read ↗

Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer.Semantic proximity Read ↗

Strong family history of uterine leiomyomatosis warrants fumarate hydratase mutation screening.Semantic proximity Read ↗

Hereditary Leiomyomatosis and Renal Cell Cancer.Semantic proximity Read ↗

Novel Fumarate Hydratase Mutation in Siblings With Early Onset Uterine Leiomyomas and Hereditary Leiomyomatosis and Renal Cell Cancer Syndrome.Semantic proximity Read ↗

Mutations in the fumarate hydratase gene cause hereditary leiomyomatosis and renal cell cancer in families in North America.Semantic proximity Read ↗

Genetic heterogeneity among uterine leiomyomata: insights into malignant progression.Semantic proximity Read ↗

Morphologic and Molecular Characteristics of Uterine Leiomyomas in Hereditary Leiomyomatosis and Renal Cancer (HLRCC) SyndromeSemantic proximity Read ↗

Integrated genetic and clinical investigation of autosomal dominant hereditary uterine leiomyomas: genotype-phenotype correlation in a pakistani family.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.