Article
Which has superior acid-suppressive effect, 10 mg omeprazole once daily or 20 mg famotidine twice daily? Effects of single or repeated administration in Japanese Helicobacter pylori-negative CYP2C19 extensive metabolizers.
Digestive diseases and sciences - 1 Feb 2007
Shimatani Tomohiko, Inoue Masaki, Kuroiwa Tomoko, Moriwaki Mutsuko, Xu Jing, Ikawa Kazuro, Morikawa Norifumi, Tazuma Susumu
Abstract excerpt
Low-dose omeprazole is superior to full-dose famotidine in maintenance therapy for gastroesophageal reflux disease, whereas "on-demand" famotidine is more effective for relief of episodes of heartburn. To explain this apparent discrepancy, intragastric pH was measured for 24-hr seven times in eig...
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