Article
Association of ATM activation and DNA repair with induced radioresistance after low-dose irradiation.
Radiation protection dosimetry - 1 Sept 2015
Enns L, Rasouli-Nia A, Hendzel M, Marples B, Weinfeld M
Abstract excerpt
Mammalian cells often exhibit a hyper-radiosensitivity (HRS) to radiation doses <20 cGy, followed by increased radioresistance (IRR) at slightly higher doses (∼20-30 cGy). Here, the influence of DNA double-strand break repair (DSBR) on IRR was examined. The failure of Ataxia telangiectasia (AT) cells to undergo IRR reported by others was confirmed. Flow cytometric analysis indicated that normal cells fail to show...
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