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Article

Kinetics of gene expression and bone remodelling in the clinical phase of collagen-induced arthritis

4 Mar 2015

Abstract excerpt

INTRODUCTION: Pathological bone changes differ considerably between inflammatory arthritic diseases and most studies have focused on bone erosion. Collagen-induced arthritis (CIA) is a model for rheumatoid arthritis, which, in addition to bone erosion, demonstrates bone formation at the time of clinical manifestations. The objective of this study was to use this model to characterise the histological and...

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PMID: 25889670
DOI: 10.1186/s13075-015-0531-7

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