Article
Improving the computational efficiency of fully Bayes inference and assessing the effect of misspecification of hyperparameters in whole-genome prediction models.
Genetics, selection, evolution : GSE - 7 Mar 2015
Yang Wenzhao, Chen Chunyu, Tempelman Robert J
Abstract excerpt
BACKGROUND: The reliability of whole-genome prediction models (WGP) based on using high-density single nucleotide polymorphism (SNP) panels critically depends on proper specification of key hyperparameters. A currently popular WGP model labeled BayesB specifies a hyperparameter π, that is `loosely used to describe the proportion of SNPs that are in linkage disequilibrium (LD) with causal variants. The remaining...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
