Article
HNF1B polymorphism influences the prognosis of endometrial cancer patients: a cohort study.
BMC cancer - 7 Apr 2015
Mandato Vincenzo Dario, Farnetti Enrico, Torricelli Federica, Abrate Martino, Casali Bruno, Ciarlini Gino, Pirillo Debora, Gelli Maria Carolina, Nicoli Davide, Grassi Mario, LA Sala Giovanni Battista, Palomba Stefano
Abstract excerpt
BACKGROUND: HNF1B (formerly known as TCF2) gene encodes for a transcription factor that regulates gene expression involved in normal mesodermal and endodermal developments. A close association between rs4430796 polymorphism of HNF1B gene and decreased endometrial cancer (EC) risk has been demonstrated. The aim of the current study was to test the hypothesis that rs4430796 polymorphism can influence the prognosis...
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