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Article

Prediction of long noncoding RNA functions with co-expression network in esophageal squamous cell carcinoma

23 Mar 2015

Abstract excerpt

BACKGROUND: Long non-coding RNAs (lncRNAs) are pervasively transcribed in the genome. They have important regulatory functions in chromatin remodeling and gene expression. Dysregulated lncRNAs have been studied in cancers, but their role in esophageal squamous cell carcinoma (ESCC) remains largely unknown. We have conducted lncRNA expression screening and a genome-wide analysis of lncRNA and coding gene...

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PMID: 25885227
DOI: 10.1186/s12885-015-1179-z

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